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Administration of SB239063 Ameliorates Ovariectomy-Induced Bone Loss via Suppressing Osteoclastogenesis in Mice

Activation of osteoclast formation and function is crucial for the development of osteolytic diseases such as osteoporosis. RANKL (receptor activator of nuclear factor-κB ligand) activates NF-κB (nuclear factor κB), MAPK (mitogen-activated protein kinase), and NFATc1 (nuclear factor of activated T-c...

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Detalles Bibliográficos
Autores principales: Huang, Bao, Wang, Jiasheng, Zhang, Xuyang, Xie, Ziang, Wu, Hao, Liu, Junhui, Jie, Zhiwei, Zhao, Xiangde, Qin, An, Fan, Shunwu, Chen, Jian, Zhao, Fengdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704231/
https://www.ncbi.nlm.nih.gov/pubmed/31474861
http://dx.doi.org/10.3389/fphar.2019.00900