Conserved structural RNA domains in regions coding for cleavage site motifs in hemagglutinin genes of influenza viruses

The acquisition of a multibasic cleavage site (MBCS) in the hemagglutinin (HA) glycoprotein is the main determinant of the conversion of low pathogenic avian influenza viruses into highly pathogenic strains, facilitating HA cleavage and virus replication in a broader range of host cells. In nature,...

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Detalles Bibliográficos
Autores principales: Gultyaev, Alexander P, Richard, Mathilde, Spronken, Monique I, Olsthoorn, René C L, Fouchier, Ron A M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704317/
https://www.ncbi.nlm.nih.gov/pubmed/31456885
http://dx.doi.org/10.1093/ve/vez034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704317/
https://www.ncbi.nlm.nih.gov/pubmed/31456885
http://dx.doi.org/10.1093/ve/vez034

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