Matrine induces apoptosis in acute myeloid leukemia cells by inhibiting the PI3K/Akt/mTOR signaling pathway

Matrine has been demonstrated to exert anticancer effects on acute myeloid leukemia (AML) cell lines. However, the mechanisms of matrine in AML remain largely unknown. The present study investigated the anticancer effects and underlying mechanisms of matrine on human AML cells in vitro. THP-1 cell l...

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Detalles Bibliográficos
Autores principales: Hao, Yanmei, Zhang, Nan, Wei, Nannan, Yin, Hongmei, Zhang, Yingjie, Xu, Hui, Zhu, Chaomang, Li, Duojie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704321/
https://www.ncbi.nlm.nih.gov/pubmed/31452769
http://dx.doi.org/10.3892/ol.2019.10649

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704321/
https://www.ncbi.nlm.nih.gov/pubmed/31452769
http://dx.doi.org/10.3892/ol.2019.10649

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