Sustainable Asymmetric Organolithium Chemistry: Enantio‐ and Chemoselective Acylations through Recycling of Solvent, Sparteine, and Weinreb “Amine”

The well‐established Hoppe–Beak chemistry, which involves enantioselective generation of organolithium compounds in the presence of (−)‐sparteine, was revisited and applied to unprecedented acylations with Weinreb amides to access highly enantioenriched α‐oxyketones and cyclic α‐aminoketones. Recycl...

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Detalles Bibliográficos
Autores principales: Monticelli, Serena, Holzer, Wolfgang, Langer, Thierry, Roller, Alexander, Olofsson, Berit, Pace, Vittorio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704367/
https://www.ncbi.nlm.nih.gov/pubmed/30614208
http://dx.doi.org/10.1002/cssc.201802815

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704367/
https://www.ncbi.nlm.nih.gov/pubmed/30614208
http://dx.doi.org/10.1002/cssc.201802815

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