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SALM4 regulates angiogenic functions in endothelial cells through VEGFR2 phosphorylation at Tyr1175

Angiogenesis depends on VEGF-mediated signaling. However, the regulatory mechanisms and functions of individual VEGF receptor 2 (VEGFR2) phosphorylation sites remain unclear. Here, we report that synaptic adhesion-like molecule 4 (SALM4) regulates a specific VEGFR2 phosphorylation site. SALM4 silenc...

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Detalles Bibliográficos
Autores principales: Kim, Dong Young, Park, Jeong Ae, Kim, Yeomyung, Noh, Minyoung, Park, Songyi, Lie, Eunkyung, Kim, Eunjoon, Kim, Young-Myeong, Kwon, Young-Guen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704462/
https://www.ncbi.nlm.nih.gov/pubmed/31170000
http://dx.doi.org/10.1096/fj.201802516RR