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Streptococcus agalactiae disrupts P-glycoprotein function in brain endothelial cells

Bacterial meningitis is a serious life threatening infection of the CNS. To cause meningitis, blood–borne bacteria need to interact with and penetrate brain endothelial cells (BECs) that comprise the blood–brain barrier. BECs help maintain brain homeostasis and they possess an array of efflux transp...

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Detalles Bibliográficos
Autores principales: Kim, Brandon J., McDonagh, Maura A., Deng, Liwen, Gastfriend, Benjamin D., Schubert-Unkmeir, Alexandra, Doran, Kelly S., Shusta, Eric V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704684/
https://www.ncbi.nlm.nih.gov/pubmed/31434575
http://dx.doi.org/10.1186/s12987-019-0146-5