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Streptococcus agalactiae disrupts P-glycoprotein function in brain endothelial cells
Bacterial meningitis is a serious life threatening infection of the CNS. To cause meningitis, blood–borne bacteria need to interact with and penetrate brain endothelial cells (BECs) that comprise the blood–brain barrier. BECs help maintain brain homeostasis and they possess an array of efflux transp...
Autores principales: | Kim, Brandon J., McDonagh, Maura A., Deng, Liwen, Gastfriend, Benjamin D., Schubert-Unkmeir, Alexandra, Doran, Kelly S., Shusta, Eric V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704684/ https://www.ncbi.nlm.nih.gov/pubmed/31434575 http://dx.doi.org/10.1186/s12987-019-0146-5 |
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