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Development of a high-throughput γ-H2AX assay based on imaging flow cytometry

BACKGROUND: Measurement of γ-H2AX foci levels in cells provides a sensitive and reliable method for quantitation of the radiation-induced DNA damage response. The objective of the present study was to develop a rapid, high-throughput γ-H2AX assay based on imaging flow cytometry (IFC) using the Image...

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Detalles Bibliográficos
Autores principales: Lee, Younghyun, Wang, Qi, Shuryak, Igor, Brenner, David J., Turner, Helen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704696/
https://www.ncbi.nlm.nih.gov/pubmed/31438980
http://dx.doi.org/10.1186/s13014-019-1344-7