SOX2 promotes hypoxia-induced breast cancer cell migration by inducing NEDD9 expression and subsequent activation of Rac1/HIF-1α signaling

BACKGROUND: Hypoxia, a major condition associated with the tumor microenvironment, stimulates the migration of cancer cells. SOX2 is a powerful transcription factor that shows higher expression in several cancers, however, its role in hypoxia-induced breast cancer cell migration remains largely elus...

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Detalles Bibliográficos
Autores principales: Wang, Yueyuan, Bibi, Maria, Min, Pengxiang, Deng, Wenjie, Zhang, Yujie, Du, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704701/
https://www.ncbi.nlm.nih.gov/pubmed/31462898
http://dx.doi.org/10.1186/s11658-019-0180-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704701/
https://www.ncbi.nlm.nih.gov/pubmed/31462898
http://dx.doi.org/10.1186/s11658-019-0180-y

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