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Genetic polymorphisms and epigenetic regulation of survivin encoding gene, BIRC5, in multiple sclerosis patients

BACKGROUND: The persistent the inflammatory condition in multiple sclerosis (MS) may due to the aberrant regulation of the elimination of the pathogenic autoreactive lymphocytes through apoptosis. Survivin, encoded by the BIRC5 gene, has been indicated to be involved in the regulation of apoptosis....

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Detalles Bibliográficos
Autores principales: Rahban, Dariush, Mohammadi, Forogh, Alidadi, Mehdi, Ghantabpour, Taha, Kheyli, Pedram Abbasi Ghasem, Ahmadi, Majid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704704/
https://www.ncbi.nlm.nih.gov/pubmed/31438837
http://dx.doi.org/10.1186/s12865-019-0312-1