Reduction of metastatic potential by inhibiting EGFR/Akt/p38/ERK signaling pathway and epithelial-mesenchymal transition after carbon ion exposure is potentiated by PARP-1 inhibition in non-small-cell lung cancer

BACKGROUND: Carbon ion ((12)C) radiotherapy is becoming very promising to kill highly metastatic cancer cells keeping adjacent normal cells least affected. Our previous study shows that combined PARP-1 inhibition with (12)C ion reduces MMP-2,-9 synergistically in HeLa cells but detailed mechanism ar...

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Detalles Bibliográficos
Autores principales: Chowdhury, Priyanka, Dey, Payel, Ghosh, Sourav, Sarma, Asitikantha, Ghosh, Utpal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704719/
https://www.ncbi.nlm.nih.gov/pubmed/31438892
http://dx.doi.org/10.1186/s12885-019-6015-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704719/
https://www.ncbi.nlm.nih.gov/pubmed/31438892
http://dx.doi.org/10.1186/s12885-019-6015-4

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