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Codelivery of mRNA with α-Galactosylceramide Using a New Lipopolyplex Formulation Induces a Strong Antitumor Response upon Intravenous Administration

[Image: see text] Recently, the use of mRNA-based vaccines for cancer immunotherapy has gained growing attention. Several studies have shown that mRNA delivered in a vectorized format can generate a robust and efficient immune response. In this work, a new lipopolyplex vector (multi-LP), incorporati...

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Detalles Bibliográficos
Autores principales: Guevara, Maria L., Jilesen, Zachary, Stojdl, David, Persano, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705043/
https://www.ncbi.nlm.nih.gov/pubmed/31460428
http://dx.doi.org/10.1021/acsomega.9b00489