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Irisin Enhances Doxorubicin-Induced Cell Apoptosis in Pancreatic Cancer by Inhibiting the PI3K/AKT/NF-κB Pathway

BACKGROUND: Irisin, a myokine released from skeletal muscle following exercise, has been shown to affect the proliferation of some cancer cells and chemosensitivity of anticancer drugs like doxorubicin (DOX). However, the effects of irisin on chemosensitivity in pancreatic cancer (PC) cells have not...

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Detalles Bibliográficos
Autores principales: Liu, Jiayu, Huang, Yibing, Liu, Yu, Chen, Yuxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705179/
https://www.ncbi.nlm.nih.gov/pubmed/31412018
http://dx.doi.org/10.12659/MSM.917625