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Impact of Cancer-Associated Fibroblast on the Radiation-Response of Solid Xenograft Tumors

Increasing evidence indicates that the heterogeneous tumor stroma supports therapy resistance at multiple levels. Fibroblasts, particularly cancer-associated fibroblasts (CAFs) are critical components of the tumor stroma. However, the impact of CAFs on the outcome of radiotherapy (RT) is poorly unde...

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Detalles Bibliográficos
Autores principales: Steer, Alizée, Cordes, Nils, Jendrossek, Verena, Klein, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705217/
https://www.ncbi.nlm.nih.gov/pubmed/31475157
http://dx.doi.org/10.3389/fmolb.2019.00070