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Structures of human ENT1 in complex with adenosine reuptake inhibitors

The human Equilibrative Nucleoside Transporter 1 (hENT1), a member of the SLC29 family, plays crucial roles in adenosine signaling, cellular uptake of nucleoside for DNA and RNA synthesis, and nucleoside-derived anticancer and antiviral drug transport in human. Because of its central role in adenosi...

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Detalles Bibliográficos
Autores principales: Wright, Nicholas J., Lee, Seok-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705415/
https://www.ncbi.nlm.nih.gov/pubmed/31235912
http://dx.doi.org/10.1038/s41594-019-0245-7