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Structures of human ENT1 in complex with adenosine reuptake inhibitors
The human Equilibrative Nucleoside Transporter 1 (hENT1), a member of the SLC29 family, plays crucial roles in adenosine signaling, cellular uptake of nucleoside for DNA and RNA synthesis, and nucleoside-derived anticancer and antiviral drug transport in human. Because of its central role in adenosi...
Autores principales: | Wright, Nicholas J., Lee, Seok-Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705415/ https://www.ncbi.nlm.nih.gov/pubmed/31235912 http://dx.doi.org/10.1038/s41594-019-0245-7 |
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