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Intrathecal B-cell accumulation and axonal damage distinguish MRI-based benign from aggressive onset in MS
OBJECTIVE: We explored the incremental value of adding multiple disease activity biomarkers in CSF and serum for distinguishing MRI-based benign from aggressive MS in early disease course. METHODS: Ninety-three patients diagnosed with clinically isolated syndrome (CIS) or early MS were divided into...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705631/ https://www.ncbi.nlm.nih.gov/pubmed/31454774 http://dx.doi.org/10.1212/NXI.0000000000000595 |