Intrathecal B-cell accumulation and axonal damage distinguish MRI-based benign from aggressive onset in MS

OBJECTIVE: We explored the incremental value of adding multiple disease activity biomarkers in CSF and serum for distinguishing MRI-based benign from aggressive MS in early disease course. METHODS: Ninety-three patients diagnosed with clinically isolated syndrome (CIS) or early MS were divided into...

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Detalles Bibliográficos
Autores principales: Engel, Sinah, Friedrich, Michaela, Muthuraman, Muthuraman, Steffen, Falk, Poplawski, Alicia, Groppa, Sergiu, Bittner, Stefan, Zipp, Frauke, Luessi, Felix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705631/
https://www.ncbi.nlm.nih.gov/pubmed/31454774
http://dx.doi.org/10.1212/NXI.0000000000000595

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