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Transposon-insertion sequencing screens unveil requirements for EHEC growth and intestinal colonization

Enterohemorrhagic Escherichia coli O157:H7 (EHEC) is an important food-borne pathogen that colonizes the colon. Transposon-insertion sequencing (TIS) was used to identify genes required for EHEC and E. coli K-12 growth in vitro and for EHEC growth in vivo in the infant rabbit colon. Surprisingly, ma...

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Detalles Bibliográficos
Autores principales: Warr, Alyson R., Hubbard, Troy P., Munera, Diana, Blondel, Carlos J., Abel zur Wiesch, Pia, Abel, Sören, Wang, Xiaoxue, Davis, Brigid M., Waldor, Matthew K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705877/
https://www.ncbi.nlm.nih.gov/pubmed/31404118
http://dx.doi.org/10.1371/journal.ppat.1007652