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Large-scale production of lentiviral vectors using multilayer cell factories

Lentiviral-mediated gene therapy has been proposed for the treatment of a range of diseases, and due to its genome integration properties, it offers the potential for long-lasting benefit from a once-off treatment. Production methods for pre-clinical studies in animal models, and ultimately for huma...

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Detalles Bibliográficos
Autores principales: Rout-Pitt, Nathan, McCarron, Alexandra, McIntyre, Chantelle, Parsons, David, Donnelley, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of Biological Methods 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706103/
https://www.ncbi.nlm.nih.gov/pubmed/31453241
http://dx.doi.org/10.14440/jbm.2018.236