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Large-scale production of lentiviral vectors using multilayer cell factories
Lentiviral-mediated gene therapy has been proposed for the treatment of a range of diseases, and due to its genome integration properties, it offers the potential for long-lasting benefit from a once-off treatment. Production methods for pre-clinical studies in animal models, and ultimately for huma...
Autores principales: | Rout-Pitt, Nathan, McCarron, Alexandra, McIntyre, Chantelle, Parsons, David, Donnelley, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Journal of Biological Methods
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706103/ https://www.ncbi.nlm.nih.gov/pubmed/31453241 http://dx.doi.org/10.14440/jbm.2018.236 |
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