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Development and implementation of a cell-based assay to discover agonists of the nuclear receptor REV-ERBα

The nuclear receptors are transcription factors involved in the regulation of a variety of physiological processes whose activity can be modulated by binding to relevant small molecule ligands. Their dysfunction has been shown to play a role in disease states such as diabetes, cancer, inflammatory d...

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Detalles Bibliográficos
Autores principales: Hering, Yuliya, Berthier, Alexandre, Duez, Helene, Lefebvre, Philippe, Deprez, Benoit, Gribbon, Philip, Wolf, Markus, Reinshagen, Jeanette, Halley, Francoise, Hannemann, Juliane, Böger, Rainer, Staels, Bart, Gul, Sheraz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of Biological Methods 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706147/
https://www.ncbi.nlm.nih.gov/pubmed/31453244
http://dx.doi.org/10.14440/jbm.2018.244