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Development and implementation of a cell-based assay to discover agonists of the nuclear receptor REV-ERBα
The nuclear receptors are transcription factors involved in the regulation of a variety of physiological processes whose activity can be modulated by binding to relevant small molecule ligands. Their dysfunction has been shown to play a role in disease states such as diabetes, cancer, inflammatory d...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Journal of Biological Methods
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706147/ https://www.ncbi.nlm.nih.gov/pubmed/31453244 http://dx.doi.org/10.14440/jbm.2018.244 |