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A three-dimensional co-culture system to investigate macrophage-dependent tumor cell invasion

Macrophages infiltrate cancers and promote progression to invasion and metastasis. To directly examine tumor-associated macrophages (TAMs) and tumor cells interacting and co-migrating in a three-dimensional (3D) environment, we have developed a co-culture model that uses a PyVmT mouse mammary tumor-...

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Detalles Bibliográficos
Autores principales: Dwyer, Amy R., Ellies, Lesley G., Holme, Andrea L., Pixley, Fiona J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: jbm 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706153/
https://www.ncbi.nlm.nih.gov/pubmed/31453214
http://dx.doi.org/10.14440/jbm.2016.132