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Imaging of glucose metabolism by 13C-MRI distinguishes pancreatic cancer subtypes in mice

Metabolic differences among and within tumors can be an important determinant in cancer treatment outcome. However, methods for determining these differences non-invasively in vivo is lacking. Using pancreatic ductal adenocarcinoma as a model, we demonstrate that tumor xenografts with a similar gene...

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Detalles Bibliográficos
Autores principales: Kishimoto, Shun, Brender, Jeffrey R, Crooks, Daniel R, Matsumoto, Shingo, Seki, Tomohiro, Oshima, Nobu, Merkle, Hellmut, Lin, Penghui, Reed, Galen, Chen, Albert P, Ardenkjaer-Larsen, Jan Henrik, Munasinghe, Jeeva, Saito, Keita, Yamamoto, Kazutoshi, Choyke, Peter L, Mitchell, James, Lane, Andrew N, Fan, Teresa WM, Linehan, W Marston, Krishna, Murali C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706239/
https://www.ncbi.nlm.nih.gov/pubmed/31408004
http://dx.doi.org/10.7554/eLife.46312