A single K(+)-binding site in the crystal structure of the gastric proton pump

The gastric proton pump (H(+),K(+)-ATPase), a P-type ATPase responsible for gastric acidification, mediates electro-neutral exchange of H(+) and K(+) coupled with ATP hydrolysis, but with an as yet undetermined transport stoichiometry. Here we show crystal structures at a resolution of 2.5 Å of the...

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Detalles Bibliográficos
Autores principales: Yamamoto, Kenta, Dubey, Vikas, Irie, Katsumasa, Nakanishi, Hanayo, Khandelia, Himanshu, Fujiyoshi, Yoshinori, Abe, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706254/
https://www.ncbi.nlm.nih.gov/pubmed/31436534
http://dx.doi.org/10.7554/eLife.47701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706254/
https://www.ncbi.nlm.nih.gov/pubmed/31436534
http://dx.doi.org/10.7554/eLife.47701

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