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Targeted Downregulation of kdm4a Ameliorates Tau-engendered Defects in Drosophila melanogaster
BACKGROUND: Tauopathies, a class of neurodegenerative diseases that includes Alzheimer's disease (AD), are characterized by the deposition of neurofibrillary tangles composed of hyperphosphorylated tau protein in the human brain. As abnormal alterations in histone acetylation and methylation sh...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Academy of Medical Sciences
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706347/ https://www.ncbi.nlm.nih.gov/pubmed/31436053 http://dx.doi.org/10.3346/jkms.2019.34.e225 |