Sp1-regulated expression of p11 contributes to motor neuron degeneration by membrane insertion of TASK1

Disruption in membrane excitability contributes to malfunction and differential vulnerability of specific neuronal subpopulations in a number of neurological diseases. The adaptor protein p11, and background potassium channel TASK1, have overlapping distributions in the CNS. Here, we report that the...

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Detalles Bibliográficos
Autores principales: García-Morales, Victoria, Rodríguez-Bey, Guillermo, Gómez-Pérez, Laura, Domínguez-Vías, Germán, González-Forero, David, Portillo, Federico, Campos-Caro, Antonio, Gento-Caro, Ángela, Issaoui, Noura, Soler, Rosa M., Garcera, Ana, Moreno-López, Bernardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706379/
https://www.ncbi.nlm.nih.gov/pubmed/31439839
http://dx.doi.org/10.1038/s41467-019-11637-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706379/
https://www.ncbi.nlm.nih.gov/pubmed/31439839
http://dx.doi.org/10.1038/s41467-019-11637-4

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