Cargando…
Sp1-regulated expression of p11 contributes to motor neuron degeneration by membrane insertion of TASK1
Disruption in membrane excitability contributes to malfunction and differential vulnerability of specific neuronal subpopulations in a number of neurological diseases. The adaptor protein p11, and background potassium channel TASK1, have overlapping distributions in the CNS. Here, we report that the...
Autores principales: | García-Morales, Victoria, Rodríguez-Bey, Guillermo, Gómez-Pérez, Laura, Domínguez-Vías, Germán, González-Forero, David, Portillo, Federico, Campos-Caro, Antonio, Gento-Caro, Ángela, Issaoui, Noura, Soler, Rosa M., Garcera, Ana, Moreno-López, Bernardo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706379/ https://www.ncbi.nlm.nih.gov/pubmed/31439839 http://dx.doi.org/10.1038/s41467-019-11637-4 |
Ejemplares similares
-
Targeting autotaxin impacts disease advance in the SOD1‐G93A mouse model of amyotrophic lateral sclerosis
por: Gento‐Caro, Ángela, et al.
Publicado: (2021) -
Lysophosphatidic Acid and Several Neurotransmitters Converge on Rho-Kinase 2 Signaling to Manage Motoneuron Excitability
por: García-Morales, Victoria, et al.
Publicado: (2021) -
Membrane-Derived Phospholipids Control Synaptic Neurotransmission and Plasticity
por: García-Morales, Victoria, et al.
Publicado: (2015) -
IGF-1, Inflammation and Retinal Degeneration: A Close Network
por: Arroba, Ana I., et al.
Publicado: (2018) -
Survival motor neuron protein and neurite degeneration are regulated by Gemin3 in spinal muscular atrophy motoneurons
por: Miralles, Maria P., et al.
Publicado: (2022)