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Linkage of CD8(+) T cell exhaustion with high-fat diet-induced tumourigenesis
Obesity increases the risk of cancer. Increased levels of hormones (such as oestrogen, insulin, insulin-like growth factor, and leptin), free fatty acid-induced production of reactive oxygen species, an altered intestinal microbiome and chronic inflammation are known to be associated with an increas...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706391/ https://www.ncbi.nlm.nih.gov/pubmed/31439906 http://dx.doi.org/10.1038/s41598-019-48678-0 |