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Linkage of CD8(+) T cell exhaustion with high-fat diet-induced tumourigenesis

Obesity increases the risk of cancer. Increased levels of hormones (such as oestrogen, insulin, insulin-like growth factor, and leptin), free fatty acid-induced production of reactive oxygen species, an altered intestinal microbiome and chronic inflammation are known to be associated with an increas...

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Detalles Bibliográficos
Autores principales: Kado, Tomonobu, Nawaz, Allah, Takikawa, Akiko, Usui, Isao, Tobe, Kazuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706391/
https://www.ncbi.nlm.nih.gov/pubmed/31439906
http://dx.doi.org/10.1038/s41598-019-48678-0