Crystal structures of cholera toxin in complex with fucosylated receptors point to importance of secondary binding site

Cholera is a life-threatening diarrhoeal disease caused by the human pathogen Vibrio cholerae. Infection occurs after ingestion of the bacteria, which colonize the human small intestine and secrete their major virulence factor – the cholera toxin (CT). The GM1 ganglioside is considered the primary r...

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Detalles Bibliográficos
Autores principales: Heim, Joel B., Hodnik, Vesna, Heggelund, Julie E., Anderluh, Gregor, Krengel, Ute
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706398/
https://www.ncbi.nlm.nih.gov/pubmed/31439922
http://dx.doi.org/10.1038/s41598-019-48579-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706398/
https://www.ncbi.nlm.nih.gov/pubmed/31439922
http://dx.doi.org/10.1038/s41598-019-48579-2

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