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Allylpyrocatechol, isolated from betel leaf ameliorates thyrotoxicosis in rats by altering thyroid peroxidase and thyrotropin receptors

Allylpyrocatechol (APC) was isolated from betel leaf and its possible role in L-thyroxin (L-T(4))-induced thyrotoxic rats was evaluated. The disease condition, thyrotoxicosis was confirmed by higher levels of thyroid hormones and low thyrotropin (TSH) in serum. Increased hepatic activities of 5′-mon...

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Detalles Bibliográficos
Autores principales: Panda, Sunanda, Sikdar, Malabika, Biswas, Sagarika, Sharma, Rajesh, Kar, Anand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706422/
https://www.ncbi.nlm.nih.gov/pubmed/31439949
http://dx.doi.org/10.1038/s41598-019-48653-9