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Epitope Mapping by NMR of a Novel Anti-Aβ Antibody (STAB-MAb)

Alzheimer´s Disease (AD) is one of the most common neurodegenerative disorders worldwide. Excess of β-amyloid (Aβ), a peptide with a high propensity to misfold and self-aggregate, is believed to be the major contributor to the observed neuronal degeneration and cognitive decline in AD. Here, we char...

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Detalles Bibliográficos
Autores principales: Posado-Fernández, Adrián, Afonso, Cláudia F., Dória, Gonçalo, Flores, Orfeu, Cabrita, Eurico J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706428/
https://www.ncbi.nlm.nih.gov/pubmed/31439854
http://dx.doi.org/10.1038/s41598-019-47626-2