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SMAR1 favors immunosurveillance of cancer cells by modulating calnexin and MHC I expression
Down-regulation or loss of MHC class I expression is a major mechanism used by cancer cells to evade immunosurveillance and increase their oncogenic potential. MHC I mediated antigen presentation is a complex regulatory process, controlled by antigen processing machinery (APM) dictating immune respo...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706529/ https://www.ncbi.nlm.nih.gov/pubmed/31422285 http://dx.doi.org/10.1016/j.neo.2019.07.002 |