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Dexmedetomidine exerts dual effects on human annulus fibrosus chondrocytes depending on the oxidative stress status
Dexmedetomidine (Dex) is an anesthetic widely used in lumbar discectomy, but its effect on chondrocytes remains unclear. Dex is speculated to promote cartilage degeneration by activating α-2 adrenergic receptor. However, the antioxidative and anti-inflammatory effects of Dex implied the potential ch...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Portland Press Ltd.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706599/ https://www.ncbi.nlm.nih.gov/pubmed/31383789 http://dx.doi.org/10.1042/BSR20190419 |