Id1 Stabilizes Epiblast Identity by Sensing Delays in Nodal Activation and Adjusting the Timing of Differentiation

Controlling responsiveness to prevailing signals is critical for robust transitions between cell states during development. For example, fibroblast growth factor (FGF) drives naive pluripotent cells into extraembryonic lineages before implantation but sustains pluripotency in primed cells of the pos...

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Detalles Bibliográficos
Autores principales: Malaguti, Mattias, Migueles, Rosa Portero, Blin, Guillaume, Lin, Chia-Yi, Lowell, Sally
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706657/
https://www.ncbi.nlm.nih.gov/pubmed/31204172
http://dx.doi.org/10.1016/j.devcel.2019.05.032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706657/
https://www.ncbi.nlm.nih.gov/pubmed/31204172
http://dx.doi.org/10.1016/j.devcel.2019.05.032

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