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Id1 Stabilizes Epiblast Identity by Sensing Delays in Nodal Activation and Adjusting the Timing of Differentiation
Controlling responsiveness to prevailing signals is critical for robust transitions between cell states during development. For example, fibroblast growth factor (FGF) drives naive pluripotent cells into extraembryonic lineages before implantation but sustains pluripotency in primed cells of the pos...
Autores principales: | Malaguti, Mattias, Migueles, Rosa Portero, Blin, Guillaume, Lin, Chia-Yi, Lowell, Sally |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706657/ https://www.ncbi.nlm.nih.gov/pubmed/31204172 http://dx.doi.org/10.1016/j.devcel.2019.05.032 |
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