Enhancer Priming Enables Fast and Sustained Transcriptional Responses to Notch Signaling

Information from developmental signaling pathways must be accurately decoded to generate transcriptional outcomes. In the case of Notch, the intracellular domain (NICD) transduces the signal directly to the nucleus. How enhancers decipher NICD in the real time of developmental decisions is not known...

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Detalles Bibliográficos
Autores principales: Falo-Sanjuan, Julia, Lammers, Nicholas C., Garcia, Hernan G., Bray, Sarah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706658/
https://www.ncbi.nlm.nih.gov/pubmed/31378591
http://dx.doi.org/10.1016/j.devcel.2019.07.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706658/
https://www.ncbi.nlm.nih.gov/pubmed/31378591
http://dx.doi.org/10.1016/j.devcel.2019.07.002

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