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Enhancer Priming Enables Fast and Sustained Transcriptional Responses to Notch Signaling
Information from developmental signaling pathways must be accurately decoded to generate transcriptional outcomes. In the case of Notch, the intracellular domain (NICD) transduces the signal directly to the nucleus. How enhancers decipher NICD in the real time of developmental decisions is not known...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706658/ https://www.ncbi.nlm.nih.gov/pubmed/31378591 http://dx.doi.org/10.1016/j.devcel.2019.07.002 |