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Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation

Clathrin-mediated endocytosis (CME) is key to maintaining the transmembrane protein composition of cells’ limiting membranes. During mammalian CME, a reversible phosphorylation event occurs on Thr156 of the μ2 subunit of the main endocytic clathrin adaptor, AP2. We show that this phosphorylation eve...

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Detalles Bibliográficos
Autores principales: Wrobel, Antoni G., Kadlecova, Zuzana, Kamenicky, Jan, Yang, Ji-Chun, Herrmann, Torsten, Kelly, Bernard T., McCoy, Airlie J., Evans, Philip R., Martin, Stephen, Müller, Stefan, Sroubek, Filip, Neuhaus, David, Honing, Stefan, Owen, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706699/
https://www.ncbi.nlm.nih.gov/pubmed/31430451
http://dx.doi.org/10.1016/j.devcel.2019.07.017