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Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation
Clathrin-mediated endocytosis (CME) is key to maintaining the transmembrane protein composition of cells’ limiting membranes. During mammalian CME, a reversible phosphorylation event occurs on Thr156 of the μ2 subunit of the main endocytic clathrin adaptor, AP2. We show that this phosphorylation eve...
Autores principales: | Wrobel, Antoni G., Kadlecova, Zuzana, Kamenicky, Jan, Yang, Ji-Chun, Herrmann, Torsten, Kelly, Bernard T., McCoy, Airlie J., Evans, Philip R., Martin, Stephen, Müller, Stefan, Sroubek, Filip, Neuhaus, David, Honing, Stefan, Owen, David J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706699/ https://www.ncbi.nlm.nih.gov/pubmed/31430451 http://dx.doi.org/10.1016/j.devcel.2019.07.017 |
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