Does Polyvinylpyrrolidone Improve the Chemical Stability of Cilazapril in Solid State?

In this study a solid dispersion and a physical mixture of cilazapril (CIL) with a biopolymer - polyvinylpyrrolidone (PVP) as a carrier were prepared so as to investigate the effect of PVP on the stability of CIL. CIL is unstable in solid state and decomposes rapidly under humid conditions. It requi...

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Detalles Bibliográficos
Autores principales: Regulska, Katarzyna, Regulski, Miosz, Wzgarda, Anna, Kotowska, Aleksandra, Ignasiak, Aleksandra, Ćwiertnia, Barbara, Stanisz, Beata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706751/
https://www.ncbi.nlm.nih.gov/pubmed/31531043
http://dx.doi.org/10.22037/ijpr.2019.1100640

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706751/
https://www.ncbi.nlm.nih.gov/pubmed/31531043
http://dx.doi.org/10.22037/ijpr.2019.1100640

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