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Does Polyvinylpyrrolidone Improve the Chemical Stability of Cilazapril in Solid State?
In this study a solid dispersion and a physical mixture of cilazapril (CIL) with a biopolymer - polyvinylpyrrolidone (PVP) as a carrier were prepared so as to investigate the effect of PVP on the stability of CIL. CIL is unstable in solid state and decomposes rapidly under humid conditions. It requi...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Shaheed Beheshti University of Medical Sciences
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706751/ https://www.ncbi.nlm.nih.gov/pubmed/31531043 http://dx.doi.org/10.22037/ijpr.2019.1100640 |