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Biosynthesis of an Anti-Addiction Agent from the Iboga Plant

[Image: see text] (−)-Ibogaine and (−)-voacangine are plant derived psychoactives that show promise as treatments for opioid addiction. However, these compounds are produced by hard to source plants, making these chemicals difficult for broad-scale use. Here we report the complete biosynthesis of (−...

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Detalles Bibliográficos
Autores principales: Farrow, Scott C., Kamileen, Mohamed O., Caputi, Lorenzo, Bussey, Kate, Mundy, Julia E. A., McAtee, Rory C., Stephenson, Corey R. J., O’Connor, Sarah E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706869/
https://www.ncbi.nlm.nih.gov/pubmed/31364847
http://dx.doi.org/10.1021/jacs.9b05999