Influence of batch effect correction methods on drug induced differential gene expression profiles

BACKGROUND: Batch effects were not accounted for in most of the studies of computational drug repositioning based on gene expression signatures. It is unknown how batch effect removal methods impact the results of signature-based drug repositioning. Herein, we conducted differential analyses on the...

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Detalles Bibliográficos
Autores principales: Zhou, Wei, Koudijs, Karel K. M., Böhringer, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706913/
https://www.ncbi.nlm.nih.gov/pubmed/31438848
http://dx.doi.org/10.1186/s12859-019-3028-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706913/
https://www.ncbi.nlm.nih.gov/pubmed/31438848
http://dx.doi.org/10.1186/s12859-019-3028-6

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