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Influence of batch effect correction methods on drug induced differential gene expression profiles
BACKGROUND: Batch effects were not accounted for in most of the studies of computational drug repositioning based on gene expression signatures. It is unknown how batch effect removal methods impact the results of signature-based drug repositioning. Herein, we conducted differential analyses on the...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706913/ https://www.ncbi.nlm.nih.gov/pubmed/31438848 http://dx.doi.org/10.1186/s12859-019-3028-6 |