The DNA Methylation Inhibitor Zebularine Controls CD4(+) T Cell Mediated Intraocular Inflammation

CD4(+) T cell mediated uveitis is conventionally treated with systemic immunosuppressive agents, including corticosteroids and biologics targeting key inflammatory cytokines. However, their long-term utility is limited due to various side effects. Here, we investigated whether DNA methylation inhibi...

Descripción completa

Detalles Bibliográficos
Autores principales: Zou, Yanli, Hu, Xiao, Schewitz-Bowers, Lauren P., Stimpson, Madeleine, Miao, Li, Ge, Xiaofei, Yang, Liu, Li, Yan, Bible, Paul W., Wen, Xiaofeng, Li, Jing Jing, Liu, Yizhi, Lee, Richard W. J., Wei, Lai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706956/
https://www.ncbi.nlm.nih.gov/pubmed/31475011
http://dx.doi.org/10.3389/fimmu.2019.01950

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706956/
https://www.ncbi.nlm.nih.gov/pubmed/31475011
http://dx.doi.org/10.3389/fimmu.2019.01950

Ejemplares similares