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A human endogenous retrovirus encoded protease potentially cleaves numerous cellular proteins

BACKGROUND: A considerable portion of the human genome derives from retroviruses inherited over millions of years. Human endogenous retroviruses (HERVs) are usually severely mutated, yet some coding-competent HERVs exist. The HERV-K(HML-2) group includes evolutionarily young proviruses that encode t...

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Detalles Bibliográficos
Autores principales: Rigogliuso, Giuseppe, Biniossek, Martin L., Goodier, John L., Mayer, Bettina, Pereira, Gavin C., Schilling, Oliver, Meese, Eckart, Mayer, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707001/
https://www.ncbi.nlm.nih.gov/pubmed/31462935
http://dx.doi.org/10.1186/s13100-019-0178-z