IL-4 Mediated Resistance of BALB/c Mice to Visceral Leishmaniasis Is Independent of IL-4Rα Signaling via T Cells

Previous studies infecting global IL-4Rα(−/−), IL-4(−/−), and IL-13(−/−)mice on a BALB/c background with the visceralizing parasite Leishmania donovani have shown that the T helper 2 cytokines, IL-4, and IL-13, play influential but not completely overlapping roles in controlling primary infection. S...

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Detalles Bibliográficos
Autores principales: McFarlane, Emma, Mokgethi, Thabang, Kaye, Paul M., Hurdayal, Ramona, Brombacher, Frank, Alexander, James, Carter, Katharine C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707061/
https://www.ncbi.nlm.nih.gov/pubmed/31475014
http://dx.doi.org/10.3389/fimmu.2019.01957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707061/
https://www.ncbi.nlm.nih.gov/pubmed/31475014
http://dx.doi.org/10.3389/fimmu.2019.01957

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