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IL-4 Mediated Resistance of BALB/c Mice to Visceral Leishmaniasis Is Independent of IL-4Rα Signaling via T Cells
Previous studies infecting global IL-4Rα(−/−), IL-4(−/−), and IL-13(−/−)mice on a BALB/c background with the visceralizing parasite Leishmania donovani have shown that the T helper 2 cytokines, IL-4, and IL-13, play influential but not completely overlapping roles in controlling primary infection. S...
Autores principales: | McFarlane, Emma, Mokgethi, Thabang, Kaye, Paul M., Hurdayal, Ramona, Brombacher, Frank, Alexander, James, Carter, Katharine C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707061/ https://www.ncbi.nlm.nih.gov/pubmed/31475014 http://dx.doi.org/10.3389/fimmu.2019.01957 |
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