The Transcriptional and Protein Profile From Human Infected Neuroprogenitor Cells Is Strongly Correlated to Zika Virus Microcephaly Cytokines Phenotype Evidencing a Persistent Inflammation in the CNS

Zika virus (ZIKV) infection during pregnancy is associated with microcephaly, a congenital malformation resulting from neuroinflammation and direct effects of virus replication on the developing central nervous system (CNS). However, the exact changes in the affected CNS remain unknown. Here, we sho...

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Detalles Bibliográficos
Autores principales: Lima, Morganna C., de Mendonça, Leila R., Rezende, Antonio M., Carrera, Raquel M., Aníbal-Silva, Conceição E., Demers, Matthew, D'Aiuto, Leonardo, Wood, Joel, Chowdari, Kodavali V., Griffiths, Michael, Lucena-Araujo, Antonio R., Barral-Netto, Manoel, Azevedo, Elisa A. N., Alves, Renan W., Farias, Pablo C. S., Marques, Ernesto T. A., Castanha, Priscila M. S., Donald, Claire L., Kohl, Alain, Nimgaonkar, Vishwajit L., Franca, Rafael F. O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707094/
https://www.ncbi.nlm.nih.gov/pubmed/31474994
http://dx.doi.org/10.3389/fimmu.2019.01928

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707094/
https://www.ncbi.nlm.nih.gov/pubmed/31474994
http://dx.doi.org/10.3389/fimmu.2019.01928

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